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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105700dc1a11ec677e669cd168a9feb785ebc6c795adba2f1111f1c2a9669a91' 
  AND token = 'fRoh6XXXSdxIb+Tk6UJicCUHBmyvxGixokR7BjlhZoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}