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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f012d29b6932be8fb72e1f994868f2b27f36fd1c635de1f770735a6995b91e01' 
  AND token = '14pZn64dMljm9LMfswxVezS6a9k6lGHR29RJC+iklfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}