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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec20af94f53fa5e2677da0042ab2466184f5a7bfbee214fae8d659a945dc2075' 
  AND token = 'Ry1hXYlk1XIDWC4RMonTKPSf3PyVO0HWZghI8m//y7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}