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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab8e7d9508b3c4fcdf27f95560e15cae737773e58c3ce460862091c33098717' 
  AND token = 'JmMHklj70zkY0o83P+4mxxv9sj2DJskWrHSlHuIc4KU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}