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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728cead6ee9404914f890dba4163a244f86c944d8643b9de644bc3c8a849e53e' 
  AND token = 'qXgQOlR/DRoVENcM5IwDZ/aT+ff8Bz9qe/0lkXw4U4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}