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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0456fb79035ee0a7b4912c114af446b27f98cca0dea3c254459d3a7703f20cb3' 
  AND token = 'nzlOmvWnq5NOzVPr2bQMN4zgEiEd9Muy/3DMuL+Jok0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}