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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15e033b987176462f18ae050c7b598c2a6cf1d978e6d0cbbdad06514a11e161b' 
  AND token = 'iebODWJUIyFHrCzi8IY9AZH/2h1DVqtftMN2H+aFrrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}