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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b348246bb257df75fc2c7b26689fec781ebb10a751df9dbbbfc0b2913f474082' 
  AND token = 'heqz+0SsOonN+1imvbSzQqtY3QsNmM/xs2ievm5Mpqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}