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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b75b942661f81a3ab0bd55315510de83531512282ff6b7fe4a78995fac307b2' 
  AND token = 'yXwzzSXPtfqNxOLXyots5BOvd+WFoVStnm4UpenCNWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}