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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e00e5e69b6e3d25b7654e4953d12a3830b6a51ad9643a50d51b95e2b6551b858' 
  AND token = 'xRuS0g0lP3spU78tferXMJGs6kf9Xt0PFX2edGnG3KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}