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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52fc7eee4c6e82e12647ef562f29fc8d0a56a099d064425cc8a91eb52e9be59' 
  AND token = 'iqgKQtJyfC/bBMPeM0lWHEu+SkALghD98y1BOcQbBZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}