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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33b2d796471e8551f39bb06785572f090b88230249696b141235e8fc0fd383c6' 
  AND token = '9U/iTZcaoLxT1dII0k1jCTbkSD6qb0MyrhvInLLA4Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}