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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48747ed52a7ab8d3f8440e2ac32b185c065c5ad7739730867ae41c1c9beb884d' 
  AND token = 'gbvs3gtnm/w7AmkLtNfRp5WJvw0DpsXhpFKP5eH9OXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}