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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb245441a5b0e45a25d285a3ef86afab8c8d2fef793c8f72a2773df755fd4f5' 
  AND token = 'nUiRfenvK87PKrbAKxWn5r7BkqMJbiEuz0h/73cYcck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}