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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8975e09f9f6617a063801580c5623a775a099e685d6eba0795c23b866e4785d' 
  AND token = 'dJOLtlc/0iI4AhurDoL5Dt28VUE13nykcTuzYc9Q67w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}