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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3358265493eb58e8e9ba8b70bed254a1490fcd95ba769194122b5be9a1ec2c47' 
  AND token = 'VFn4pKYhR2rSSp95GQ5rdSGr2q5cZmmTF0MM1ZIk5Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}