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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e48e1e4b73ffb7f0bd5453d4ef1acf4d03fee349776b7cee7f524a85cf9c2163' 
  AND token = 'C7NTkBrFUGDhqr4ZEUbrbpaO1ZuMGMAo4aKSBxFAuwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}