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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e28b1419a47f52cc27e9a65f42ca07e252186d744413c72e2e138db88aab8074' 
  AND token = '2GTO8mOKOqx0cT3EotdrkpeFxNe8YwfD4eG3FQejXa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}