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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e64ea9690a4959aea4fb5f633c42cb5e2ddef0c8d930abb07f9a6eb56e455c' 
  AND token = 'TDvsWFa8xJeiF+z2Kjym15OTHtsB/41hIs5NFB7bWds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}