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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403243fa5c0e03ff27bd9bd5990cbedc1c57c4f0929476b79fa0157ecd1aa85f' 
  AND token = 'mtXNZU8UwOWkw9s23nPT/409QDVwl/SpxCjpoM+/cPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}