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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '584747aa90d77e8472de98633c3df883d21279639c53ac1e7a41c02a4f81e9c8' 
  AND token = 'rtWUJfa3/uZIKzEH/xeN+XyL1aF6vEEE+fA6YJOyPdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}