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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b66ef7a9be05bdec79662a146d766203c71d0fbbc5a0d750623bce7685c3d1a' 
  AND token = '/sPebvtzOUFp7qGFpRV5Tx6SrBDBCkfVYkT8qtgT9aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}