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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ae5e1dfe9ffa2a5a793d8b8bb7cdfb805974f4e82c695da54c185bc2c822d1e' 
  AND token = 'sZk335yMSNc5ND0qrp2bulHrPrzhV4P8QVc3GqY5Ooo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}