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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4de40cfb6ffd08338ccb31265ea087b843c116a279b9d8eda37d596f7dc6855' 
  AND token = 'RRmQvUCu7o+FKrxcOsVs9rfyJLEMWvHkv1gUdc3xNZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}