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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26deb7877f8bc6eb7179840710b1fcf06ff2e546934f2621e03c8a33c2514420' 
  AND token = 'iIiRTfUoARHRihrsXibQeUyosBJjjTLKZ8elW7hC6Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}