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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb5b80b1df4e575d4e42da3a88c02dd3c7542af52cb306349c807a73b4856320' 
  AND token = 'zFBTZYaiskfOFOjRbOtGcFaSfD2MQYrnE2z5XMJoD0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}