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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4932c8310c0138c2b07dfbe945c1f0169537568c04e6dbc11e0f314f85e7043' 
  AND token = 'u4KtqmIYdBAHIlKTJ992gQyBLRguCcN2DIq9gO0b9lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}