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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1389bcded185d24295397b98f052a496c74e01d80abd4373c15b3c682135626f' 
  AND token = 'CCKwYosNvy6TfTD+Pm8RBXN19WbkLtN0VjrUklcpjbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}