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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be4c08151c672d1dcca7a6201d7da5bde7141e9fca095a3fc9f1c38fab753a52' 
  AND token = 'YdJpFl1FS/44rA6wp9HZSL0nYN4p9dd8Xdpk2MNoK+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}