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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d0cc8b7822b3bf785433f42a959ff99712e3421a8d72b61099bc4d51ba17da2' 
  AND token = 'H3Zx6jvrS+0/BnEeVQXCl8bSHensnbRPe9eDJ/nD5ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}