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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110a1642019b7801e17c60d30c9bdb085bada80d6caffb4c91784662a072e0bc' 
  AND token = '66YmoC3fmKB5XmakB5FUa6Wcln8TmySL9WkcLl03K84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}