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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022bf6f437224631ef838be9cd4f92c01324000cf0ae3b5fa5789bed0f5dd1d9' 
  AND token = 'fjf/tsp1DUENdv63imgm42SsY3KNU5o2PfL4ea5+44c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}