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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cc768b8eaa7f7be65369dd3ea0a956449006da32209b37a103d626e46022a4c' 
  AND token = 'bJnp5Kibmor35l//+aqzETDYLOhRa3mCApNlDcxEdyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}