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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3731202844525cc2989e4bebc6187e303cd4b09ba86182bf52fb8c1d1098857a' 
  AND token = 'R82WMee27odZd5CwBY05SSVH6j3+9greu46cX32lRpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}