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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2271d5a604d656e036cc8d75989c06c5b7bdf459960ae90c4b0d9a5def366356' 
  AND token = '0J2ugoUYHoEnpQPdZEz4NyrInMNT9gHMg86OmMMpqSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}