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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '954de65ed231a3e14d060636c4d68921a7a1c27e17dd1b5b2e64731f0687d0fd' 
  AND token = 'IQVqlH9/lLtnGueUV8phtzH9ANM2nU0ZgHKa5EVKisU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}