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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45bb2e0fee5d5269aab171c70a16a2cbc352c252ab4253751ac58a786410982f' 
  AND token = '88XWi3+NuTkoiMHF4+zjaQPdd92ZVd7TOgs5VLEszwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}