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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866eeed55d32846667bc2f78b833f3ed00c267f3974a6e38e2025d4d790f6e40' 
  AND token = 'IxCL2Q7Berd+zM8wwnckowkQJdgJIeYoJ6ZqYqm8sTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}