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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38aedc12c64d32cb5419c022e39255c84f195dd96a86b66c1c959335bbc252f' 
  AND token = 'B4t9yT3QBMKAHJMB/X6jC+ytp+FtJb9Vru8Y+s3AkO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}