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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8295284362d61b194c1d32343ac0271cbc89ca247060ebe2038101fc59478d' 
  AND token = 'UjPlhBW1Slc6+k26MN55bEx8iKSfEh+KCHCdqDA5/2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}