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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b110e0251cc61e7a931324fd12089ce886472ee271032cc8b8ebc1a7fbd2e3a' 
  AND token = 'U/fLl0xEH9sTb+8UPFHKiAWp+1c+nYqFedZoIlWNzqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}