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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9129ebdf5a8180fa88c1ffee033d3d340ca1ba4e695351829010f0f7b3372f36' 
  AND token = 'KEjJpB3+NgBsPSejXYoa8Kf392JfT6bjVSOAC+Lm2WY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}