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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd2f4a157a2b7bede285c00860ec8922e12a949b52761477c0f428cf022f328f' 
  AND token = 'UXjj8EYnEICSvKbQq/DsjVsxjpJ154b55woUuE7oMSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}