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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '431e1cb10bd088fa4a61eafe53e246df93964037864a295b798dfe9c0e6110ff' 
  AND token = 's74DHWdVW/Sep1Hy/F4+DiTn6kfVBViyYpKyQfCjnkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}