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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb94737dfed25b1e3d275a752de44e9e4d282b3a5d5fb454cb3e445f1ed7c18' 
  AND token = 'WvGI/yLtNUmsZhU+YheOVeruOTqIWYTXEH9KBl0d3dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}