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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66993b8bd69c0559278c6847e08fb90bf3af381055fe267327642e3a26e6822a' 
  AND token = 'nlIPk60CvGmPb1epwUM4nCFol8ICFHsdL17ajfqmkIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}