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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549b464e3f79fa807ef6ecdbeb78a7f0675b919875ed71d7f2e5b89a000450d0' 
  AND token = 'nioxF+w9GTviROZc1u1yf8ia0Swu/AEWdmzFEAkxgVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}