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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c891b39ad00767ee98183ea29f910e5c874daabc67f7fac98e21702248060576' 
  AND token = 'WAJ9j1gPZfEuy3lGb9NhLiA26rMDz8cH+nNj7g1tvnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}