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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bdcf4a517d8230d3088d995a30ecb87e2fefa4dc0c0946a73e689f51ae5941b' 
  AND token = 'E2m4R0pENpLDOAg4v4b8xpq+QHwxh5b/YzhAErGqxkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}