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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d726d4245ffc7119f60712ed75b7aafd61a372c66cdd40ab3e82a0872b25d52' 
  AND token = 'H4sijmRyCw+RqeKD0YOXYQyQIU7Kj0MVc6I8nt9PH3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}